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临床遇见口服胶态次枸橼酸铋冲剂引起女性泌乳1例,现报道如下。患者女,41a,工人,已婚。因间断上腹疼痛8a,加重4mo入院。胃镜检查:十二指肠球部小弯侧溃疡。病理:活动性胃炎。幽门螺旋菌(Helicobacterpylori)阳性。入院后给予胶态次枸橼酸铋冲剂(广东珠海丽珠药厂,批号901250)治疗,每日4次,每次1袋,wb4出现乳房胀感,未加注意。胃镜复查溃疡愈合,幽门螺旋菌阴性,出院。出院后继续每日4次服用胶态次枸橼酸铋冲剂。1wk后出现泌乳。考虑为胶态次枸橼酸铋冲剂所致。嘱停药,并做妇科检查,妇科检查正常。停药1wk后泌乳消失。再次服用胶态次枸橼酸铋冲剂,4d后再次出现泌乳现象。
Clinical encounter oral colloidal bismuth citrate granules caused by female lactation in 1 case, are reported below. Patient female, 41a, worker, married. Intermittent abdominal pain due to 8a, increased 4mo admission. Gastroscopy: duodenal bulb ulnar side of the ulcer. Pathology: active gastritis. Helicobacter pylori positive. After admission, colloidal bismuth citrate granules (Guangdong Zhuhai Lizhu Pharmaceutical Factory, lot number 901250) were treated 4 times a day, each time a bag, wb4 breast swelling, did not pay attention. Gastroscopy review of ulcer healing, Helicobacter pylori negative, discharged. Continue to take colloidal bismuth citrate granules 4 times a day after discharge. After 1wk lactation. Considered colloidal bismuth citrate granules due. Huan stop medicine, and gynecological examination, gynecological examination was normal. After 1wk withdrawal of milk disappeared. Again taking colloidal bismuth sub-citrate, 4d again after the phenomenon of lactation.