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目的:探讨内镜鼻窦手术(ESS)后应用双黄连液冲洗鼻腔的疗效。方法:2001年8月~2004年8月ESS治疗的Ⅱ型慢性鼻窦炎鼻息肉患者201例,术后随机分为双黄连组(用双黄连冲洗)和生理盐水对照组,随访6个月以上,比较2组的疗效。结果:术后双黄连组的治愈率、总有效率分别与对照组比较,差异均有统计学意义(均P<0.05)。2组中并发广泛性中鼻甲息肉样变者之间的有效率差异无统计学意义(P>0.05)。结论:双黄连粉针剂冲洗液对创口愈合、消除黏膜水肿具有促进作用,能提高ESS临床疗效,安全性好。并发广泛性中鼻甲息肉样变者临床疗效与选择的冲洗液无关,只有处理好病变中鼻甲,方可提高疗效。
Objective: To investigate the efficacy of Shuanghuanglian solution in nasal cavity after endoscopic sinus surgery (ESS). Methods: 201 patients with type Ⅱ chronic sinusitis and nasal polyps treated with ESS from August 2001 to August 2004 were randomly divided into Shuanghuanglian group (treated with Shuanghuanglian) and saline control group, followed up for more than 6 months , Comparing the efficacy of two groups. Results: The cure rate and total effective rate of Shuanghuanglian group after operation were significantly lower than those of the control group (all P <0.05). There was no significant difference between the two groups in the prevalence of extensive middle turbinate polyp-like change (P> 0.05). Conclusion: Shuanghuanglian injection can improve wound healing and mucosal edema, improve the clinical efficacy and safety of ESS. Consecutive extensive middle turbinate polypoid change clinical efficacy and choice of irrigating fluid has nothing to do, only to deal with lesions in the middle turbinate, can improve the curative effect.