It is a challenge to confirm chronic mesenteric ischemia(CMI) as a cause of gastrointestinal(GI) symptoms such as postprandial epigastric bloating,anorexia,and debilitating weight loss.Endovascular intervention for CMI has been gaining popularity because of the high morbidity associated with surgical revascularization.However,in EVI for superior mesenteric artery(SMA) occlusion,the transfemoral approach is limited by difficulty in coaxial alignment of the guiding catheter,which leads to insufficient back-up support.Herein,we report on a 58-year-old male patient with chronic total occlusion of the SMA,which was successfully revascularized by endovascular intervention via the left radial artery.Transradial endovascular therapy may be another treatment option for the treatment of CMI. It is a challenge to confirm chronic mesenteric ischemia (CMI) as a cause of gastrointestinal (GI) symptoms such as postprandial epigastric bloating, anorexia, and debilitating weight loss. Endovascular intervention for CMI has been gaining popularity because of the high morbidity associated with surgical revascularization. Despite, in EVI for superior mesenteric artery (SMA) occlusion, the transfemoral approach is limited by difficulty in coaxial alignment of the guiding catheter, which leads to insufficient back-up support. Herein, we report on a 58-year-old male patient with chronic total occlusion of the SMA, which was successfully revascularized by endovascular intervention via the left radial artery. Transradial endovascular therapy may be another another treatment option for the treatment of CMI.