已知垂体肿瘤可向前颅窝、视丘下部、鞍旁两侧、后颅窝、蝶窦内等多方向生长,扩展至额叶底面或颞叶内时,可引起癫痫发作。但以癫痫大发作为首发症状的垂体肿瘤很罕见,未见报导。1979年我院曾收治一例巨大垂体肿瘤,无明显视损害,又无垂体功能的改变,而以癫痫大发作起病,临床诊断颇为困难。现报告和讨论如下: Pituitary tumors are known to the anterior cranial fossa, hypothalamus, parasellar sides, posterior fossa, sphenoid sinus and other multi-directional growth, extended to the frontal or temporal lobe, can cause seizures. However, the first symptom of epileptic seizures of pituitary tumors is very rare, has not been reported. In 1979, our hospital had admitted a huge pituitary tumor, no obvious visual damage, and no change in pituitary function, and the onset of epileptic seizures, clinical diagnosis is quite difficult. The report and discussion are as follows: