目的:了解围手术期抗菌药物的应用现状。方法:对143例围手术期患者抗菌药物应用进行回顾性调查。结果:94例应用抗菌药物(65.7%);术前30 min~2 h用药31例(33.0%),手术时间>3 h的病例均未追加第二剂抗菌药物(0%),联合用药比例56.4%,使用药物种类以三代头孢菌素/酶抑制剂最多。结论:围手术期抗菌药物的应用有不合理现象,应加强监督管理。 Objective: To understand the application status of perioperative antibacterials. Methods: The application of antimicrobial agents in 143 perioperative patients were retrospectively investigated. Results: 94 cases were treated with antimicrobial agents (65.7%); 31 cases (33.0%) were treated 30 min to 2 h before surgery and no second antibacterials (0%) were used in cases of operation time> 3 h. 56.4%, using the third generation cephalosporins / enzyme inhibitors to use the drug type. Conclusion: There are unreasonable applications of perioperative antibacterials, and supervision and management should be strengthened.