论文部分内容阅读
目的:建立妇乐消炎丸的质量控制方法。方法:采用薄层色谱法鉴别处方中忍冬藤、大青叶、大血藤。采用HPLC法测定处方中盐酸小檗碱的含量。结果:TLC法鉴别重现性好,无干扰,HPLC法测定盐酸小檗碱的含量线性关系良好。重复性、稳定性和加样回收率等均达到含量测定要求。结论:建立的TLC和HPLC法可用于该制剂的质量控制。
Objective: To establish the quality control method of Fule Leaning Pills. METHODS: Thin-layer chromatography was used to identify the Chinese toll cane, Daqingye and Sedum cannabis. The HPLC method was used to determine the content of berberine hydrochloride in the formulation. RESULTS: The TLC method showed good reproducibility and no interference. The HPLC method had good linearity in the determination of berberine hydrochloride. Reproducibility, stability, and sample recovery all met the requirements for content determination. Conclusion: The established TLC and HPLC methods can be used for the quality control of the formulation.