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增殖细胞核抗原(PCNA)是一种细胞周期相关的36kd酸性核蛋白。其含量与细胞转化程度有关。作者选择32例骨髓增生异常综合征(MDS)、20例再生障碍性贫血(AA)、15例急性髓性白血病(AML)初诊患者和12例正常人的骨髓活检标本,用抗PCNA单抗经ABC法免疫组化染色后,测定PCNA阳性细胞占有核细胞的百分率。结果:正常对照组PCNA阳性细胞占11.0％±0.7％。MDS组为
Proliferating cell nuclear antigen (PCNA) is a cell cycle-associated 36kd acidic nucleoprotein. Its content and the degree of cell transformation. Authors selected 32 cases of myelodysplastic syndrome (MDS), 20 cases of aplastic anemia (AA), 15 cases of acute myeloid leukemia (AML) newly diagnosed patients and 12 normal bone marrow biopsy specimens with anti-PCNA monoclonal antibody After ABC immunohistochemical staining, the percentage of PCNA positive cells possessing nuclear cells was determined. Results: PCNA positive cells in normal control group accounted for 11.0% ± 0.7%. MDS group is