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目的 研究TSGF在肺癌、食管癌诊断、疗效判定中的应用价值。方法 应用放射免疫学方法测定肺部良性病变患者及肺癌、食管癌患者手术前、后血清中TSGF含量,并进行比较。结果 肺癌、食管癌TSGF诊断阳性率为73%。肺癌与肺部良性病变TSGF含量有显著差异(P<0.05),肺癌、食管癌手术前及术后30天TSGF含量有显著差异。结论 TSGF是一种广谱,敏感性高的肿瘤标志物,对于恶性肿瘤的早期诊断,疗效判定及指导治疗有重要意义。
Objective To study the application value of TSGF in the diagnosis and efficacy determination of lung cancer, esophageal cancer. Methods The serum levels of TSGF in patients with benign pulmonary lesions and patients with lung cancer and esophageal cancer before and after surgery were measured by radioimmunoassay and compared. Results The positive rate of diagnosis of lung cancer and esophageal cancer was 73%. There was a significant difference in the content of TSGF between lung cancer and lung benign lesions (P<0.05). There was a significant difference in TSGF content between lung cancer and esophageal cancer before surgery and 30 days after surgery. Conclusion TSGF is a broad-spectrum, high-sensitivity tumor marker, which has important significance for the early diagnosis, curative effect judgment and treatment of malignant tumors.