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目的:了解新疆哈萨克族妇女宫颈感染人乳头瘤病毒(HPV)基因型的分布情况。方法:取妇女宫颈的脱落细胞,利用核酸分子杂交技术检测21种HPV。结果:总共检测400例,HPV感染65例,感染率16.25%;HPV感染率排在前3位的依次是HPV 16(4.00%)、58(1.75%)和53(1.50%)。双重感染13例,占感染人数的20.00%,三重感染2例,占感染人数3.08%。HPV感染者的年龄差异无统计学意义(P>0.05)。结论:该地区妇女宫颈HPV感染常见型别为HPV 16、58、53、11、52、39、33、56、68、6,其次单一感染和混合感染均以高危型感染为主。宫颈HPV感染普遍存在各年龄段妇女中。
Objective: To understand the distribution of cervical HPV infection genotypes among Kazak women in Xinjiang. Methods: Take the exfoliated cells of the cervix in women and detect 21 kinds of HPV by nucleic acid hybridization. Results: A total of 400 cases were detected with HPV infection in 65 cases and the infection rate was 16.25%. The highest HPV infection rates were HPV 16 (4.00%), 58 (1.75%) and 53 (1.50%) in the top 3 cases. 13 cases of double infection, accounting for 20.00% of the number of infections, triple infection in 2 cases, accounting for 3.08% of the number of infections. There was no significant difference in the age of HPV infection (P> 0.05). Conclusion: The common types of cervical HPV infection in women in this area are HPV 16, 58, 53, 11, 52, 39, 33, 56, 68 and 6, followed by high-risk infection in single and mixed infections. Cervical HPV infection is prevalent in women of all ages.