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利用基因重组技术获得的生技霉素对胚胎影响的研究结果表明，生技霉素经口服给药的三个剂量组和阳性对照环磷酰胺组小鼠孕鼠体重均未受明显影响，但环磷酰胺组吸收胎率和死胎率明显增加，活胎率减少，环磷酰胺对胎鼠有明显致畸作用（Ｐ＜０．００１）。生技霉素大剂量对胚胎有一定毒性，所致吸收胎比阴性对照有所增加，但对胎鼠未见致畸作用
The results of the study on the effects of biochemcimin on embryos obtained by gene recombination technology showed that the body weight of pregnant mice in the three dose groups and the positive control cyclophosphamide group orally administered with biochemcimin were not significantly affected, Cyclophosphamide group significantly increased the rate of fetus and stillbirth, the rate of live fetus decreased, and cyclophosphamide had significant teratogenic effects on fetus (P <0.001). The high dose of biotechycin has certain toxicity to the embryo, resulting in an increase in the number of absorbed fetus compared with the negative control, but no teratogenic effect on the fetus