肝窦是不连续毛细血管 ,为通透性最大的血窦之一 ,其内皮细胞扁而薄 ,上有发达的窗孔 ,且窗孔无隔膜 ,整个细胞呈筛型状态。透射电镜在正常肝窦内皮外看不到有基底膜存在 ,如用特殊方法可显示少量网状纤维或 型胶原 ( - C)。肝纤维化过程中肝窦内皮窗孔逐渐减少或消失 ,内皮 Hepatic sinusoid is a discontinuous capillary, one of the most permeable sinusoids. Its endothelial cells are flat and thin. There are well-developed holes in the liver sinusoid, and no diaphragm is found in the fenestration. The entire cell is in the form of a sieve. Transmission electron microscopy in the normal sinusoidal endothelial can not see the presence of basement membrane, such as using special methods can show a small amount of reticular fibers or collagen (- C). Liver fibrosis during sinusoidal endothelial fenestration gradually reduced or disappeared, the endothelium