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目的:观察熊去氧胆酸胶囊应用于治疗原发性胆汁性肝硬化的临床疗效.方法:选取我院原发性胆汁性肝硬化患者60例分为观察组与对照组,对照组实施常规保肝治疗,观察组在此基础上加用熊去氧胆酸胶囊治疗.结果:观察组患者的肝区不适、腹胀、乏力、黄疸等临床症状较对照组明显缓解,治疗总有效率明显高于对照组,差异有统计学意义(P<0.05).结论:使用熊去氧胆酸胶囊对原发性胆汁性肝硬化进行治疗,能够有效缓解患者临床症状,具有更为理想的临床治疗效果.“,”To observe ursodeoxycholic acid used in the clinical efficacy of the treatment of primary biliary cirrhosis. Methods: our hospital with primary biliary cirrhosis 60 patients were divided into the observation group and the control group, the control group conventional liver treatment, the observation group on this basis plus ursodeoxycholic acid treatment. Results:The patients liver area discomfort, bloating, fatigue, jaundice and other clinical symptoms eased significantly compared with the control group, the total treatment was significantly higher efficiency, and the difference was statisticaly significant (P <0.05). Conclusion: the use of ursodeoxycholic acid for treatment of primary biliary cirrhosis, can effectively aleviate clinical symptoms in patients with more desirable clinical outcomes.