目的分析连云港市手足口病重症病例流行病学特征,为手足口病重症防制提供科学依据。方法应用描述流行病学和Logistic回归分析对2009-2012年连云港市手足口病重症病例的流行特征及危险因素进行分析。结果重症病例男性多于女性,<3岁占84.39%;散居儿童占92.48%;4-8月份为重症发病高峰期;全市8个县区均有重症病例报告。重症病例EV71阳性占61.85%。结论手足口病为连云港市儿童常见病多发病,应对3岁以下散居儿童家长针对性地开展宣传教育;提高医疗机构的早期诊断能力,同时早期监测手足口病重症危险因素,降低病重率和死亡率。 Objective To analyze the epidemiological characteristics of HFMD in Lianyungang City and provide a scientific basis for the prevention of HFMD. Methods Epidemiology and Logistic regression analysis were used to analyze the epidemiological characteristics and risk factors of severe HFMD cases in Lianyungang from 2009 to 2012. Results Male patients were more serious than female patients in severe cases, <3 years old, accounting for 84.39%. Diaspora accounted for 92.48%. From April to August, they were the peak of severe illness. Eight districts and districts of the city reported severe cases. Severe cases EV71 positive accounted for 61.85%. Conclusions Hand-foot-mouth disease is common in children in Lianyungang City. It is necessary to carry out publicity and education for parents of diaspora children under 3 years of age in order to improve the early diagnosis ability of medical institutions. At the same time, early monitoring HFRS, mortality rate.