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惠氏软膏是医院皮肤科常用制剂之一。上海市医院制剂手册收载的含测法为双相滴定法;实用医院制剂收载的含测法为加热液化后直接滴定法,以中性乙醇为溶媒。本文介绍加热液化后直接测定法,以蒸馏水为溶媒。 1 原理:根据苯甲酸和水杨酸溶于沸水的性质,用较多量的蒸馏水,用水溶加热至惠氏软膏被蒸馏水完全溶解后,用N/10 NaOH液滴定至终点。每1 ml N/10 NaOH
Wyeth ointment is one of the commonly used preparations in the hospital dermatology. Shanghai Hospital Preparation Manual contained contained biphasic titration method; practical preparations contained in hospital preparations measured by direct titration heating liquefaction to neutral ethanol as the vehicle. This article describes the direct measurement of heated liquefaction to distilled water as the vehicle. 1 Principle: According to the nature of benzoic acid and salicylic acid dissolved in boiling water, with a larger amount of distilled water, heated with water until Wyeth ointment is completely dissolved in distilled water, and titrated to the end with N / 10 NaOH solution. Per 1 ml N / 10 NaOH