对于院内获得性肺炎,抗生素的剂量不足是造成患者预后不好的主要因素,并且可能筛选出抗生素耐药的G菌和M R S A。降阶梯治疗是一种抗感染的经验性治疗方案,即开始抗感染治疗选用单一、广谱、强效的抗生素,以尽量覆盖可能导致感染的病菌,之后根据微生物学检查和药敏结果调整抗生 For nosocomial pneumonia, inadequate doses of antibiotics are a major contributor to poor prognosis in patients, and antibiotic-resistant G and MRS may be screened. Step-down therapy is an anti-infective empirical treatment that begins with anti-infective therapy using a single, broad-spectrum, potent antibiotic to cover as few germs as possible and then adjust to antibiotics based on microbiological tests and susceptibility results