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目的观察探讨新辅助疗法联合前列腺癌根治术治疗前列腺临床癌的临床疗效,总结其临床经验和临床应用价值。方法选取我院2009年1月至2011年1月前列腺临床癌的患者20例,均先采取新辅助治疗,然后行前列腺癌根治术,对其临床病历资料进行回顾性分析。结果 20例患者显效12例,有效6例,无效2例,术后并发症3例(术后3个月出现轻度的压力性尿失禁有2例,6个月出现轻度的压力性尿失禁有1例,均能自行恢复,无需特殊处理),无1例远期复发,总有效率为90.0%。结论新辅助疗法联合前列腺癌根治术治疗前列腺临床癌的临床疗效较为理想,能够有助于提高手术成功率,减少术后并发症发生和远期复发,安全性提高,值得临床合理推广和应用。
Objective To investigate the clinical effect of neoadjuvant therapy combined with radical prostatectomy on prostate cancer and to summarize its clinical experience and clinical value. Methods Twenty patients with clinical prostate cancer from January 2009 to January 2011 in our hospital were enrolled in this study. Neoadjuvant treatment was given first and then radical prostatectomy was performed. The clinical records were retrospectively analyzed. Results Twenty patients were markedly effective in 12 cases, effective in 6 cases, ineffective in 2 cases and postoperative complications in 3 cases (mild stress urinary incontinence occurred in 3 months and mild pressured urine in 6 months Incontinence in 1 case, both self-recovery, without special treatment), no one case of long-term recurrence, the total effective rate was 90.0%. Conclusions Neoadjuvant therapy combined with radical prostatectomy for the treatment of prostate cancer is an ideal clinical outcome, which can help to improve the success rate of surgery, reduce postoperative complications and long-term recurrence, improve the safety, and worthy of clinical promotion and application.