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目的探讨去氧孕烯炔雌醇片(商品名:妈富隆)治疗功能失调性子宫出血的临床治疗效果。方法 90例功能失调性子宫出血患者,随机分为治疗组和对照组,每组45例。治疗组采用口服妈富隆药物治疗,对照组采用临床传统药物(口服己烯雌酚)治疗。观察两组患者的治疗效果以及药物的不良反应。结果治疗组患者平均止血时间(3.5±1.3)d短于对照组(6.7±1.8)d,差异有统计学意义(P<0.05)。治疗后3个月治疗组止血后重建月经周期比例42.2%优于对照组13.3%,差异有统计学意义(P<0.05)。治疗组不良反应发生率13.33%低于对照组31.11%,差异有统计学意义(P<0.05)。结论妈富隆治疗功能失调性子宫出血的止血效果明显,可辅助重建月经周期,且药物不良反应少,治疗效果良好。
Objective To investigate the clinical efficacy of ethinyl estradiol desogestrel (commercial name: Marvelon) in the treatment of dysfunctional uterine bleeding. Methods 90 patients with dysfunctional uterine bleeding were randomly divided into treatment group and control group, 45 cases in each group. The treatment group was treated with oral Marvelon, while the control group was treated with clinical traditional medicine (diethylstilbestrol). To observe the treatment effect of two groups of patients and adverse drug reactions. Results The average hemostasis time in the treatment group was shorter than that in the control group (3.5 ± 1.3) d (6.7 ± 1.8) d, with significant difference (P <0.05). Three months after treatment, the proportion of the menstrual cycle in the treatment group after hemostasis was 42.2%, which was significantly better than that in the control group (13.3%, P <0.05). The incidence of adverse reactions in the treatment group was 13.33% lower than that in the control group (31.11%), the difference was statistically significant (P <0.05). Conclusion Marvelon treatment of dysfunctional uterine bleeding hemostatic effect is obvious, can help reconstruct the menstrual cycle, and less adverse drug reactions, the treatment effect is good.