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目的对米非司酮临床治疗子宫肌瘤患者的效果进行探讨评价。方法对60例子宫肌瘤患者给予米非司酮口服10mg/d,测定治疗前后血P、LH、E2、FSH的平均水平并进行比较治疗后各项指标明显下降(P<0.01)。结果在服药的过程中患者的闭经、贫血等症状都得到了很好的改善,其围绝经期也均都提前的过渡到自然绝经期。结论将米非司酮应用于子宫肌瘤患者的临床治疗中,其疗效确切,具有积极的临床应用价值,值得大力推广和应用。
Objective To evaluate the efficacy of mifepristone in the treatment of uterine fibroids. Methods 60 patients with uterine fibroids were given mifepristone orally 10mg / d. The levels of P, LH, E2 and FSH in blood were determined before and after treatment. The indexes of the two groups were significantly decreased after treatment (P <0.01). Results During the medication, the symptoms of amenorrhea and anemia of patients were well improved, and the perimenopausal period also advanced to the natural menopause. Conclusion The application of mifepristone in the clinical treatment of patients with uterine fibroids, the curative effect is exact, has a positive clinical value, it is worth to promote and apply.