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目的探究健脾活血中药复方联合TACE治疗肝癌的临床效果。方法将60例中晚期肝癌患者分为两组,每组30例。使用TACE法加以治疗,观察组患者以此为基础,加用健脾活血中药,对比治疗后不良反应,近期疗效,中医症候积分改善以及KPS评分情况。结果经治疗后,观察组患者的近期治疗效果,中医症状积分等方面较好,毒性反应低,P<0.05。两组患者的临床有效率差异不存在统计学意义,观察组患者的临床稳定率好于对照组,P<0.05。手术前,两组患者肿瘤标志物差异无统计学意义,P<0.05。手术1个月,2个月后,对照组相比,观察组患者的肿瘤标记物较少,组间数据差异存在统计学意义,P<0.05。结论对于中晚期肝癌者,以TACE化疗方案为基础,使用健脾活血中药加以治疗,可延长患者生存时长,取得满意效果。
Objective To explore the clinical effect of Chinese herbal medicine of Jianpihuoxue combined with TACE on liver cancer. Methods Sixty patients with advanced liver cancer were divided into two groups, 30 in each group. TACE was used to treat patients in the observation group. Based on this, the spleen and blood-activating Chinese herbs were added, the adverse reactions after treatment were compared, the short-term results were improved, the scores of TCM symptoms were improved, and the KPS score was evaluated. Results After treatment, the short-term treatment effect of the observation group, TCM symptom score and other aspects were good, and the toxicity was low, P<0.05. There was no statistically significant difference in clinical efficacy between the two groups. The clinical stability rate of the observation group was better than that of the control group, P<0.05. Before surgery, there was no significant difference in tumor markers between the two groups, P<0.05. After one month and two months of surgery, compared with the control group, there were fewer tumor markers in the observation group, and there was a statistically significant difference between the two groups, P<0.05. Conclusion For advanced liver cancer patients, based on TACE chemotherapy regimen, the use of spleen-invigorating and blood-activating Chinese herbs for treatment can prolong the survival time of patients and achieve satisfactory results.