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目的观察通脉促活胶囊对兔实验性高粘滞血症的红细胞流变性的作用。方法用高分子右旋糖苷对兔造成高粘滞血症，即血瘀证动物模型，通过对动物血液粘度和红细胞流变性指标的检测，观察通脉促活胶囊的药理作用。结果通脉促活胶囊具有降低血液粘度、降低红细胞聚集指数和提高红细胞变形能力的作用、给药后，红细胞聚集指数为１４．２９±５．０６％，红细胞变形指数为４５．５８±６．４１％，和生理盐水对照组比较有显著差异（Ｐ<０．０１）。结论通脉促活胶囊具有降低兔血液粘度，增加细胞流动性，改善红细胞流变性的作用，具有预防和治疗作用。
Objective To observe the effect of Tongmai Changhuo capsule on the rheology of red blood cells in rabbits with experimental hyperviscosity. Methods High viscosity dextran was used to induce hyperviscosity in rabbits, which was the animal model of blood stasis syndrome. The pharmacological effects of Tongmaijinhuo capsules were observed by measuring blood viscosity and red blood cell rheological parameters. RESULTS: Tongmai Qihuo Capsule had the effects of lowering blood viscosity, decreasing erythrocyte aggregation index and improving red blood cell deformability. After administration, the erythrocyte aggregation index was 14.29±5.06%, and the red blood cell deformation index was 45.58±6. 41% was significantly different from the saline control group (P<0.01). Conclusion Tongmai Qihuo Capsule has the effects of preventing and treating rabbit blood viscosity, increasing cell fluidity and improving red blood cell rheology.