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从ＥｓｃｈｅｒｉｃｈｉａｃｏｌｉＭ５２４８（Ｂｉｏ２７５ｃＩ８５７ＨＩ）中，经发酵培养，离心，超声破碎，溶解，二次凝胶过滤层析，复性处理及冷冻干燥，一次获得了３６ｍｇ较高纯度的重组人白介素－２。
From Escherichia coli M5248 (Bio275cI857HI), 36mg of recombinant human interleukin-2 of higher purity was obtained in a single pass through fermentation culture, centrifugation, sonication, dissolution, secondary gel filtration chromatography, refolding and freeze-drying.