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关于结合珠蛋白类型和乳腺癌的关系,至今很少报导。Kleisbauer等(1975年)研究了不同种类癌瘤的结合珠蛋白。在435名包括乳腺癌在内的实体瘤患者中发现Hp~1基因的频率降低。可惜的是没有按瘤体的发生部位详细区分患者。本文报告109名患乳腺癌的希腊患者的各型结合珠蛋白的分布情况。血清样品由接收希腊各地患者的希腊抗癌学院的住院患者中取得。通过水平的淀粉胶电泳,使用不连续的Tris-硼酸盐缓冲系统(pH8.65),并用联苯胺染色,来分析样品。附表列出希腊患者和普通希腊人群的各型结合珠蛋白的分布。在患者和普通人群中
The relationship between haptoglobin type and breast cancer has rarely been reported so far. Kleisbauer et al. (1975) studied haptoglobin in different types of cancers. The frequency of Hp~1 gene was found to decrease in 435 solid tumor patients including breast cancer. Unfortunately, there is no detailed distinction between patients according to the location of the tumor. This article reports the distribution of various types of haptoglobin in 109 Greek patients with breast cancer. Serum samples were obtained from inpatients at the Greek Cancer Institute receiving patients from all over Greece. Samples were analyzed by horizontal starch gel electrophoresis using a discontinuous Tris-borate buffer system (pH 8.65) and stained with benzidine. The table shows the distribution of various types of haptoglobin in the Greek patients and the general Greek population. In patients and general population