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肿瘤的发生发展是个多阶段过程 ,其中基因性和基因外因素起着决定作用。近年来 ,由于广泛采用转基因动物作为实验材料 ,肿瘤形成的各个阶段的研究工作均取得了新进展 ,现就有关内容综述如下。1 增生调控肿瘤细胞最重要的特性之一是不依赖外界因素而无限增殖。目前认为肿瘤增生
The occurrence and development of tumors is a multi-stage process in which genetic and extra-genomic factors play a decisive role. In recent years, thanks to the widespread adoption of transgenic animals as experimental materials, new progress has been made in the research of tumor formation at various stages. The relevant contents are summarized below. 1 One of the most important characteristics of proliferation-regulating tumor cells is indefinite proliferation without dependence on external factors. Currently considered tumor hyperplasia