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应用静脉注射丙种球蛋白2g/kg草剂和400mg/kg连用3d治疗川崎病36例,观察其对左心功能的影响,结果治疗前所有患儿左室舒张末内径较正常儿童扩大(P<0.05);治疗后1周内前者较后者扩大更明显;病程25d后,两组左室舒张末内径与正常儿童比较无显著性差异。提示单剂量静脉注射丙种球蛋白对急性期川崎病患儿左心功能有一定影响。
Thirty-six cases of Kawasaki disease were treated with intravenous gamma globulin (2 g / kg) and 400 mg / kg combined with 3d, and their effects on left ventricular function were observed. The results showed that the left ventricular end-diastolic diameter of all children before treatment was larger than that of normal children (P < 0.05). In the first week after treatment, the former was more obvious than the latter. After 25 days of course of treatment, the left ventricular end-diastolic diameter of the two groups showed no significant difference compared with normal children. Prompt single-dose intravenous gamma globulin on acute left heart function in children with Kawasaki disease have a certain impact.