脑型脂肪酸结合蛋白(B-FABP)属于脂肪酸结合蛋白家族成员之一,主要在神经系统发育阶段的放射状胶质细胞中表达[1-2],在成年大脑组织中很少表达。其除了与脂肪酸在细胞的摄取、转运和靶向作用及神经系统发育[3-4]中起重要作用外,在中枢神经系统先天性疾病[5]、脑卒中[6-7]、脑损 Brain-type fatty acid-binding protein (B-FABP), a member of the fatty acid binding protein family, is mainly expressed in radial glial cells in the developmental stages of the nervous system [1-2] and is rarely expressed in adult brain tissues. In addition to playing an important role in the uptake, transport and targeting of fatty acids and in the development of the nervous system [3,4], fatty acids have been implicated in the CNS congenital diseases [5], stroke [6-7], brain damage