某些短效降压药如卡托普利、硝苯地平等,初次服用可能有较明显的降压效果,连续数天后降压幅度不如首次明显,但仍有降压作用。又如,某些α受体阻滞剂如哌唑嗪,首次服药可出现明显的降压效果,连续服用3～5日后血压又回升。这是由于该药的钠潴留倾向的结果,若加服利尿剂,增加水、 Some short-acting antihypertensive drugs such as captopril, nifedipine, the first administration may have a more obvious antihypertensive effect, a few days after the first step lower than the first step-down, but there are still antihypertensive effect. In another example, some α-blockers such as prazosin, the first medication may be significant antihypertensive effect, continuous taking 3 to 5 days after the blood pressure and rebound. This is due to the sodium retention of the drug as a result, if plus diuretics, increase water,