环磷酰胺是临床上常用的广谱抗肿瘤药物,但是它的毒副反应较强,因此其使用受到一定的限制。尤其是它对免疫系统,造血系统,生殖系统及遗传物质 DNA 的毒性作用,会导致机体产生极其不良的后果。为此本作者系统的研究了一系列天然植物药对环磷酰胺毒性作用的影响,发现人参茎叶总皂甙对此具有明显的对抗作用,现将实验结果报告如下。 Cyclophosphamide is a broad-spectrum antitumor drug commonly used in clinical practice, but its toxic and side effects are relatively strong, so its use is limited. In particular, its toxic effects on the immune system, hematopoietic system, reproductive system, and genetic material DNA can lead to extremely bad consequences for the body. Therefore, the author systematically studied the effects of a series of natural botanical drugs on the toxic effects of cyclophosphamide, and found that the total saponins of stems and leaves of ginseng have obvious antagonistic effects. The experimental results are reported below.