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盆腔器官脱垂(Pelvic organ prolapse,POP)是指盆腔器官和与其相邻的阴道壁突入阴道或自阴道脱出。近年涌现了不少有关POP的新观念、新理论,其中神经损伤学说也成为妇科泌尿学领域的研究热点。盆底的神经纤维可分泌多种神经肽,神经纤维的减少可减少神经肽的生成和释放,造成盆底血管改变,血流灌注不足导致肌肉萎缩变性,故将神经肽作为损伤标记,并用神经肽研究盆底功能障碍性疾病的发病机制。本文从就POP与神经肽(VIP、NPY)关系作相关综述。
Pelvic organ prolapse (Pelvic organ prolapse, POP) refers to the pelvic organs and its adjacent vaginal wall into the vaginal or vaginal prolapse. In recent years, many new ideas and theories have emerged on POP. The theory of nerve injury has also become a hot spot in the field of gynecology and urology. The nerve fibers in the pelvic floor can secrete a variety of neuropeptides. The reduction of nerve fibers can reduce the production and release of neuropeptides, resulting in pelvic vascular changes, resulting in muscle atrophy and degeneration of hypoperfusion. Therefore, Peptides to study the pathogenesis of pelvic floor dysfunction. This article reviews the relationship between POP and neuropeptides (VIP, NPY).