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目的:讨探药物涂层支架对冠状动脉多支病变的疗效。方法:对350例冠心病患者的临床资料回顾性分析,其中冠脉多支病变220例,行DES置入术148例,行CABG术72例,观察两组的疗效、并发症,并临床随访24个月。结果:随访327例患者(93.42),围手术期手术成功率均较高,两组间无差异。心力衰竭发生率CABG组高于DES组(P<0.05),死亡发生率CABG组高于DES组,但无统计学差异。24个月随访结果,再发心绞痛DES组高于CABG组(P<0.05),靶血管重建,DES组高于CABG组(P<0.05)。病死率两组之间无统计学差异。结论:对于多支冠状动脉病变患者,CABG70/72(97.22)及DES143/148(96.62)组手术成功率均较高,远期效果也较好,围手术期心力衰竭发生率较低,再发心绞痛及需血运重建者DES5/148(3.38)组高于CABG0/72(0)组。
Objective: To investigate the efficacy of drug-eluting stent on coronary artery disease. Methods: The clinical data of 350 patients with coronary heart disease were analyzed retrospectively. Among them, 220 patients had multiple coronary artery disease, 148 patients underwent DES implantation and 72 patients underwent CABG. The curative effect, complications and clinical follow-up of the two groups were observed 24 months. Results: Follow-up 327 patients (93.42), the perioperative success rate was high, no difference between the two groups. The incidence of heart failure in CABG group was higher than that in DES group (P <0.05). The incidence of death in CABG group was higher than that in DES group, but there was no significant difference. After 24-month follow-up, the angiographic resection was higher in the DES group than in the CABG group (P <0.05), and the target vessel reconstruction was higher in the DES group than in the CABG group (P <0.05). There was no significant difference in mortality between the two groups. Conclusions: The success rate of CABG70 / 72 (97.22) and DES143 / 148 (96.62) group is higher for patients with multiple coronary artery disease, the long-term effect is better, the incidence of perioperative heart failure is lower, and the recurrence Angina pectoris and those requiring revascularization were higher in the DES5 / 148 (3.38) group than in the CABG0 / 72 (0) group.