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介绍20例小儿恶性组织细胞病。大多数发病于婴幼儿期,总病程1～6个月。全部病例均有发热.肝脾肿大各18例(90%),表浅淋巴结肿大17例(85%),皮疹16例(80%)。周围血白细胞<10×10~9/L17例(85%),骨髓检查13例发现有各类型组织细胞,淋巴结活检3例,尸检3例,皮肤活检1例均证实诊断。激素治疗13例,其中1例激素加抗白Ⅰ号好转出院,追踪2月内死亡,2例采用COCP方案病情暂时缓解1～1(1/2)月后死亡,5例明确诊断后自动出院,出院随访均于1个月内死亡,2例入院不久即死亡。
Introduced 20 cases of pediatric malignant cell disease. Most of the incidence in infancy, the total duration of 1 to 6 months. All cases had fever, with hepatosplenomegaly in 18 cases (90%), superficial lymph nodes in 17 cases (85%) and rash in 16 cases (80%). Peripheral blood leukocytes <10 × 10 ~ 9 / L17 (85%), bone marrow examination in 13 cases were found in all kinds of tissue cells, lymph node biopsy in 3 cases, autopsy in 3 cases, skin biopsy in 1 case confirmed the diagnosis. Hormone therapy in 13 cases, of which 1 hormone plus anti-Bai Ⅰ improved discharge, follow-up within 2 months of death, 2 cases of COCP program temporarily relieved 1 to 1 (1/2) months after the death, 5 cases were diagnosed automatically discharged , Were discharged within 1 month after the death were hospitalized, 2 patients died soon after admission.