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目的 探讨乳腺癌化疗 ,内分泌治疗 ,化疗与内分泌治疗联合应用以及晚期乳腺癌全身治疗的最新进展。方法 复习近年的文献并对其进行综述。结果 临床上新药的不断开发明显提高乳腺癌治疗的总有效率 ,化疗与内分泌治疗联合应用的治疗效果则根据病人的受体状况 ,月经状态以及腋淋巴结受累情况而有明显差异。结论 乳腺癌药物治疗应根据病人年龄、病理分期、月经状态、受体状况等个体化特征选择不同的治疗方案。
Objective To investigate the latest developments in breast cancer chemotherapy, endocrine therapy, combined use of chemotherapy and endocrine therapy, and systemic treatment of advanced breast cancer. Methods Review recent literature and review them. Results The continuous development of new drugs in the clinic significantly improved the total effective rate of breast cancer treatment. The combined effect of chemotherapy and endocrine therapy was significantly different depending on the patient’s status of acceptors, menstrual status and axillary lymph node involvement. Conclusion Drug therapy for breast cancer should be based on the patient’s age, pathological stage, menstrual status, receptor status and other individual characteristics to choose different treatment options.