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克罗恩病(Crohn′s disease,CD)是一种病因目前尚未明确的胃肠道慢性炎性肉芽肿性疾病,其病变多见于末端回肠和临近结肠,但从口腔至肛门各段消化道均可受累,病灶呈节段性或跳跃性分布。CD好发于16~25岁的年轻人,且女性的发病率高于男性20%~30%[1]。CD患者临床可表现为程度不一的腹痛、慢性腹泻、体重减轻等,部分患者可并发肛瘘、胆囊结石等肠外表现,而其组织学表现则主要以慢性
Crohn’s disease (CD) is a chronic inflammatory granulomatous disease of the gastrointestinal tract whose etiology is not yet clear. The disease is more common in the distal ileum and the adjacent colon, but from the oral cavity to the anal digestive tract Can be involved, the lesions were segmental or jumping distribution. CD occurs in young people aged 16 to 25, and the incidence of women than men, 20% to 30% [1]. CD patients can be clinically manifested as varying degrees of abdominal pain, chronic diarrhea, weight loss, some patients may be complicated by anal fistula, gallstone and other parenteral manifestations, and its histological performance is mainly chronic