论文部分内容阅读
目的 :探讨应用血浆置换对重度高胆红素血症的临床疗效及安全性。方法 :治疗组 89例共行血浆置换治疗 2 85次 ,平均 3 2次 ,比较治疗前后临床表现 ,主要实验室检查指标及不良反应。设同期住院病情相似的病例 76例为对照组。结果 :治疗组症状明显好转 ;血TBIL、DBIL、ALT、AST明显下降 ,PTA、ALB升高 ;治愈好转率 86 5 2 %,不良反应率 3 2 63 %。对照组治愈好转率 64 47%。治愈好转病例住院时间 :治疗组 ( 2 6 5 8± 14 2 7)天 ,对照组 ( 5 1 3 9± 16 45 )天 ,两组比较有显著差异。结论 :血浆置换为高胆红素血症患者提供了较为安全有效的治疗手段
Objective: To investigate the clinical effect and safety of plasma exchange on severe hyperbilirubinemia. Methods: A total of 89 patients in the treatment group were treated with plasma exchange for 2 85 times, with an average of 32 times. The clinical manifestations, major laboratory tests and adverse reactions were compared before and after treatment. Set the same period hospitalized cases of similar cases of 76 cases as control group. Results: The symptoms in the treatment group were improved obviously. The levels of TBIL, DBIL, ALT and AST were significantly decreased, while PTA and ALB were elevated. The cure rate was 86 5 2% and the adverse reaction rate was 32 63%. The control group improved cure rate 64 47%. The cured hospitalization time: the treatment group (2658 ± 1427 days), the control group (5193 ± 1645) days, the two groups were significantly different. Conclusions: Plasma exchange provides a safe and effective treatment for patients with hyperbilirubinemia