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按药物作用机理,一般将利胆药分为两类,即作用于肝脏促进胆汁分泌的催胆药和促使胆囊收缩或胆道口括约肌弛缓、促进胆汁向十二指肠排出的排胆药。一、催胆药 (一)熊去氧胆酸(简称熊酸) 本品是催胆药中胆汁酸制剂的代表。作用机理是由于胆汁酸发挥渗透压利胆作用,即胆汁酸本身被排泄到毛细胆管内,在肝细胞与毛细胆管之间形成渗透压差而引起的。实验证明,熊酸本身在肝脏内含量增加后还具有使碳酸氢
According to the mechanism of drug action, usually divided into two types of gallbladder medicine, that is, the role of the liver to promote the secretion of bile drugs and promote urinary bladder gallbladder contraction or relaxation of the sphincter to promote the secretion of bile to the duodenum row of drugs. A reminder of the drug (a) ursodeoxycholic acid (referred to as the bear acid) This product is reminders of bile acid agents in the preparation of the drug. The mechanism of action is due to the bile acid play an infiltration of gallstones, ie, bile acid itself is excreted into the capillary bile duct, the formation of osmotic pressure difference between the liver cells and the capillary bile duct caused. Experiments show that the bear acid itself has increased in the liver after the addition of hydrogen carbonate