论文部分内容阅读
氯苯那敏和色甘酸钠(Cro)能降低豚鼠气管C神经兴奋引起的平滑肌收缩反应;渐增浓度的P物质(0.1—3.0μmol·L~(-1))引起的气管片收缩效应也可被Cro处理降低;然而支气管条的收缩反应却不受上述药物影响,但能被阿托品处理降低。提示C神经末梢兴奋平滑肌收缩的介质在豚鼠的气管和支气管部位有明显差异。
Chlorpheniramine and cromolyn sodium decreased the smooth muscle contractile response induced by C-nerve excitability in guinea-pigs. The synergistic effect of tracheal contraction induced by increasing concentrations of substance P (0.1-3.0 μmol·L -1) Decreased by Cro treatment; however, the contractile response of the bronchial strips was unaffected by the above drugs but was reduced by atropine treatment. Tip C nerve endings excited smooth muscle contraction of the medium in guinea pig trachea and bronchial parts were significantly different.