山东省是班氏丝虫病流行严重的省份,自五十年即开始了此项研究工作。首先在省内进行了流行病学调查,至六十年代确定了74个县有丝虫病流行和淡色库蚊是主要的传播媒介。其次对海群生治疗班氏丝虫病的疗效进行了60余种方案的临床和现场实验观察,最终发现4.2克7日疗法对山东班氏丝虫病疗效最好,三个疗程的微丝蚴转阴率可达95％。 Shandong Province is a province of serious epidemic of Bancroftian filariasis. This research project began in 50 years. Epidemiological surveys were first conducted in the province and in the 1960s it was determined that there were endemic filariasis and Culex pipiens pallens in 74 counties as the main media. Followed by the sea group treatment of Bancroftian filariasis curative effect of more than 60 kinds of programs of clinical and field experimental observations, and ultimately found that 4.2 grams of 7-day treatment of Shandong Bancroftian filariasis the best, three courses of microfilariae Negative rate up to 95%.