为探讨雄激素补充治疗对男性更年期综合征的疗效 ,本文通过对 6 8例诊断为男性更年期综合征病人分组 ,其中 40例作雄激素补充治疗并对其临床症状 ,血睾酮水平 ,主观抑郁症状评分作观察 ,并与 2 8例病情相同的病人予安慰剂对照。观察的病人症状改善率为 74.3% ;血睾酮水平 3周前后分别为 131.5 1± 19.12与 2 5 3.78±2 1.45 ,抑郁症状评分各指标均有较大改善。作者认为雄激素补充疗法是治疗男性更年期综合征的一种有效、安全的方法 In order to explore the effect of androgen replacement therapy on male climacteric syndrome, this paper divided 68 patients diagnosed as male climacteric syndrome, and 40 of them were treated with androgen supplementation and their clinical symptoms, serum testosterone levels, subjective depression symptoms The scores were observed and compared to 28 placebo-controlled patients. The symptom improvement rate was 74.3%. The level of serum testosterone was 131.5 1 ± 19.12 and 2 5 3.78 ± 2. 1.45 respectively before and after 3 weeks, and all the indexes of depression symptom were greatly improved. The authors believe that androgen replacement therapy is an effective and safe way to treat menopausal syndrome