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目的：探讨亚胺培南和西司他丁复方制剂对老年院内感染的疗效。方法：２０例细菌感染的老年住院病人、年龄８１．５±ｓ１．４ａ（６６－９４ａ），其中下呼吸道感染１６例，败血症３例，尿路感染１例。用亚胺培南与西司他丁复方制剂１．０－２．０ｇ／ｄ，分２－３次静脉滴注。治疗前后作血、尿常规，肝、肾功能及有关病人作胸那ｘ片，血尿、痰细菌学检查。结果：有效率为８５％，细菌清除率为８２％。未见明显不良反应。结论：亚胺培南与西司他丁复方制剂对革兰阴性杆菌及葡萄球菌所致的老年院内感染有良好的疗效。
Objective: To investigate the curative effect of imipenem and cilastatin compound on senile nosocomial infection. Methods: 20 elderly inpatients with bacterial infection, aged 81.5 ± s1.4a (66-94a), including 16 cases of lower respiratory tract infection, 3 cases of sepsis and 1 case of urinary tract infection. With imipenem and cilastatin compound preparation 1.0-2.0g / d, sub-2-3 intravenous infusion. Before and after treatment for blood, urine, liver and kidney function and the patient for chest x that hematuria, sputum bacteriological examination. Results: The effective rate was 85% and the bacterial clearance rate was 82%. No obvious adverse reactions. Conclusion: The combination of imipenem and cilastatin has good effect on Gram-negative bacilli and staphylococcus aureus infection in elderly patients.