用微波辐射技术,以葡甲胺为催化剂、水为溶剂,于800 W功率下回流反应100 min,成功对(R)-萘普生进行消旋,收率为95%。方法操作简单,反应时间短,后处理简便。 The microwave irradiation technique was used to react with (R) -naproxen and the yield was 95% with meglumine as catalyst and water as solvent, and the reaction was refluxed at 800 W for 100 min. The method has the advantages of simple operation, short reaction time and simple post-treatment.