论文部分内容阅读
目的 探讨实验室与器械检查对重症肺炎患儿肾脏损害的临床意义。方法 采用放射免疫法检测 4 1例重症肺炎患儿血、尿 β2 微球蛋白 (β2 MG)、尿微白蛋白 (MA) ,其中 38例运用彩色多普勒对各级肾动脉血流参数变化进行测定。结果 重症肺炎急性期血、尿 β2 MG、尿MA均明显高于恢复期和对照组 (P<0 .0 1) ;重症肺炎急性期肾主动脉及各分支收缩期峰值血流速度 (Vmax)、舒张期血流速度 (Vmin)均显著下降(P <0 .0 1) ,阻力指数 (RI)、搏动指数 (PI)明显升高 (P <0 .0 1)。结论 重症肺炎患儿存在肾脏损害 ,血、尿β2 MG及尿AM可以早期预测其损害程度。两种测定方法可用于重症肺炎患儿肾损害的早期诊断 ,并指导治疗。
Objective To investigate the clinical significance of laboratory and instrumental examination on renal damage in children with severe pneumonia. Methods Serum and urinary β2 microglobulin (β2 MG) and urine microalbumin (MA) were detected in 41 children with severe pneumonia by radioimmunoassay. Color Doppler was used in 38 cases of renal artery blood flow parameters Measurement was performed. Results Serum and urine β2 MG and urinary MA in patients with severe pneumonia were significantly higher than those in the recovery and control groups (P <0.01). The peak systolic velocity (Vmax) , Diastolic blood flow velocity (Vmin) were significantly decreased (P <0.01), resistance index (RI), pulsatility index (PI) was significantly increased (P <0.01). Conclusion Kidney damage, blood, urinary β2 MG and urinary AM in children with severe pneumonia can be used to predict the degree of damage early. Two determination methods can be used for early diagnosis of renal damage in children with severe pneumonia and guide the treatment.