Effect of Shenfu Injection on Serum C-reactive Protein,Calcitonin and TNF-α in Patients with Septic

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[Objectives] To explore the influence of Shenfu injection on serum C-reactive protein,blood calcium and TNF-α in the patients with septic shock. [Methods]According to admission order,78 patients with septic shock were randomly divided into control and experimental groups. Control group was treated by isopropyl epinephrine,and experimental group was treated by Shenfu injection on the basis of the control group. [Results] The total effective rate was 95. 00% for the experimental group,obviously higher than that of control group( 78. 95%)with significant difference( P < 0. 05). After 3-d treatment,the experimental group’s serum CRP and PCT levels were( 5. 83 ± 2. 51) mg / L and( 0. 97 ± 1. 12) μg / L,respectively,lower than the control group’s PCT and CRP levels of( 10. 31 ± 2. 15) mg / L and( 4. 82 ± 1. 10)μg / L,with significant difference( P < 0. 05); the experimental group’s serum TNF-α level was( 80. 83 ± 22. 51) ng / L,significantly lower than the control group’s TNF-α level of( 184. 31 ± 28. 37) ng / L,with significant difference( P < 0. 05). [Conclusions] The Shenfu injection had a good therapeutic effect on patients with septic shock,and it could improve the level of CRP,PCT and TNF-α,so it could be promoted in clinic practice. [Objectives] To explore the influence of Shenfu on serum C-reactive protein, blood calcium and TNF-α in the patients with septic shock. [Methods] According to admission order, 78 patients with septic shock were randomly divided into control and experimental groups. Control group was treated by isopropyl epinephrine, and experimental group was treated by Shenfu injection on the basis of the control group. [Results] The total effective rate was 95.00% for the experimental group, obviously higher than that of control group (78.95%) with significant difference (P <0.05). After 3-d treatment, the experimental group’s serum CRP and PCT levels were (5.83 ± 2.51) mg / L and 1. 12) μg / L, respectively, lower than the control group’s PCT and CRP levels of (10.13 ± 2.15) mg / L and (4.82 ± 1.10) μg / L, with significant difference P <0.05); the experimental group’s serum TNF-α level was (80.83 ± 22. 51) ng / L, significantly lower than the control group’s TNF-αlev el of (184. 31 ± 28. 37) ng / L, with significant difference (P <0.05). [Conclusions] The Shenfu injection had a good therapeutic effect on patients with septic shock, and it could improve the level of CRP, PCT and TNF-α, so it could be promoted in clinic practice.
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