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目的探讨纳络酮、苯巴比妥联用早期干预新生儿缺氧缺血性脑病的临床效果。方法将68例新生儿缺氧缺血性脑病患儿随机分为观察组和对照组,每组各34例。对照组给予常规治疗,观察组在常规治疗的基础上加用纳络酮、苯巴比妥,观察治疗显效率及总有效率。结果观察组与对照组的治疗显效率及总有效率经统计学处理差异有统计学意义(P<0·05)。结论纳洛酮、苯巴比妥联用早期干预新生儿缺氧缺血性脑病对提高本病治愈率、减低病死率和减少后遗症的发生有重要意义。
Objective To investigate the clinical effects of naloxone and phenobarbital combined with early intervention on neonatal hypoxic-ischemic encephalopathy. Methods Sixty-eight neonates with hypoxic-ischemic encephalopathy were randomly divided into observation group and control group, 34 cases in each group. The control group was given routine treatment. The observation group was given naloxone and phenobarbital on the basis of routine treatment, and the effective rate and total effective rate were observed. Results The effective rate of treatment and total effective rate of observation group and control group were statistically significant (P <0.05). Conclusion Naloxone and phenobarbital combined with early intervention in neonatal hypoxic-ischemic encephalopathy is of great importance to improve the cure rate, reduce mortality and reduce the incidence of sequelae.