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对质量分数为0.5%的甲氨基阿维菌素苯甲酸盐微乳剂进行急性毒性试验研究结果表明,甲维盐对大鼠经口LD50雌雄均大于5000mg/kg,经皮LD50雌雄皆大于2000mg/kg。大白兔皮肤刺激积分指数为0,大白兔眼睛加药不冲洗刺激积分指数为0,豚鼠皮肤致敏百分率为0,按“农药毒性分级标准”评价,对皮肤无刺激性,属弱致敏物,加药不冲洗对眼睛无刺激性,经口、经皮属低毒农药。试验结果表明,甲维盐对人畜低毒。环境毒性研究结果表明,甲维盐对斑马鱼LC5(096h)为27.01mg/L,根据《化学农药环境安全评价试验准则》规定的鱼毒分级标准,评价为“低毒级”;对鹌鹑以有效成分计,LD50>2000.0mg/kg.bw,根据鸟毒性分级标准,评价为“低毒级”;对蜜蜂LD5(048h)为1.96μg/蜂,根据蜜蜂毒性分级标准,评价为“中毒级”;对桑蚕LC50为1.80mg/L,根据蚕毒分级标准,评价为“高毒级”。试验结果表明,甲维盐对鱼、鸟低毒,对蚕毒性较高。
Acute toxicity test of avermectin benzoate microemulsion with a mass fraction of 0.5% showed that the oral LD50 of avermectin was more than 5000mg / kg in both sexes, and the LD50 in both sexes was greater than 2000mg / kg. Rabbit skin irritation integral index of 0, white rabbits eye dosing without flushing stimulus score of 0, guinea pig skin sensitization percentage was 0, according to “pesticide toxicity classification criteria ” evaluation, non-irritating to the skin, is weak Sensitizer, dosing does not flush the eyes without irritation, oral, percutaneous is a low toxicity pesticide. The test results show that, carbaryl salt low toxicity to humans and animals. The results of environmental toxicity showed that the toxicity of azithromycin to zebrafish LC5 (096h) was 27.01mg / L, which was evaluated as “low toxicity level” according to the classification standard of fish poisoning specified in the “Guidelines for Environmental Safety Evaluation of Chemical Pesticides” Quail active ingredient, LD50> 2000.0mg / kg.bw, according to the classification criteria of bird toxicity, as “low toxicity level”; for bees LD5 (048h) 1.96μg / bee, according to bee toxicity grading standards, For the “poisoning level”; for silkworm LC50 1.80mg / L, according to the classification of silkworm toxicity, as “highly toxic grade.” The test results show that the salt of a dimension of fish, birds, low toxicity, higher toxicity to silkworm.