论文部分内容阅读
目的探讨分支动脉粥样硬化病(BAD)与腔隙性脑梗死(LI)患者发生进展型运动障碍的风险因素。方法选取洪湖市中医医院2012年6月至2016年6月收治的215例穿支动脉区域急性脑梗死患者的临床资料,其中BAD患者135例(BAD组),LI患者80例(LI组),两组均纳入性别、年龄、血压、血糖、血脂、吸烟情况、高同型半胱氨酸、糖化血红蛋白(HbA1C)及LDL 9项预后相关因素,分析两组为进展型运动障碍的风险因素。结果经过规范治疗,BAD组有98例发展为进展型运动障碍(发生率为72.59%),LI组有25例发展为进展型运动障碍(发生率为31.25%),两组比较差异有统计学意义(P<0.05)。单因素分析显示,BAD组中进展与未进展患者的年龄、糖尿病史与Hb A1c比较差异有统计学意义(P<0.05);多因素回归分析示,BAD组的年龄和HbA1C是导致患者发展为进展型运动障碍的风险因素(P<0.05)。而LI的预后与纳入的11个因素无关(P>0.05)。结论 BAD比LI更容易发展为进展型运动障碍,其风险因素为年龄和HbA1C。
Objective To investigate the risk factors for the development of dyskinesia in patients with branch atherosclerosis (BAD) and lacunar infarction (LI). Methods The clinical data of 215 patients with acute cerebral infarction with perforating branch artery in Honghu Hospital of Traditional Chinese Medicine from June 2012 to June 2016 were retrospectively analyzed. Among them, 135 cases of BAD (BAD group), 80 cases of LI (LI group) Two groups were included gender, age, blood pressure, blood glucose, blood lipids, smoking, high homocysteine, glycosylated hemoglobin (HbA1C) and LDL 9 prognosis related factors, the two groups of risk factors for the development of dyskinesia. Results After standard treatment, 98 cases developed progressive dyskinesia (72.59%) in BAD group, 25 cases developed progressive dyskinesia (31.25%) in LI group, the difference between the two groups was statistically significant Significance (P <0.05). Univariate analysis showed that there was significant difference in age, history of diabetes and Hb A1c between patients with progression and non-progression in BAD group (P <0.05). Multivariate regression analysis showed that the age and HbA1C in BAD group led to the development of patients with Risk factors for progressive dyskinesia (P <0.05). However, the prognosis of LI was not related to the 11 factors involved (P> 0.05). Conclusions BAD is more likely to develop into progressive dyskinesia than LI, and its risk factors are age and HbA1C.