论文部分内容阅读
目的探讨焦虑抑郁与冠心病介入治疗患者预后的关系。方法入选108例冠心病并行介入治疗病人,采用汉密尔顿抑郁量表及焦虑量表评估,将入选病人分为存在焦虑抑郁状态(A组)及对照组(B组)两组,观察6个月内有无心血管事件(MACE)的发生,将影响MACE事件的因素进行对比分析,焦虑抑郁状态等与MACE事件进行多因素相关性分析。结果存在焦虑抑郁状态(A组)31例(28.7%),对照组(B组)77例(71.3%)。A组发生MACE事件(29.0%)较B组发生MACE事件(15.6%)显著增加(P<0.01),多因素回归分析提示在6个月的随访中,焦虑抑郁状态、糖尿病、高血压、吸烟是MACE事件发生的独立预测因子(焦虑抑郁,OR=0.921,95%可信区间0.845～0.963,P=0.022)。结论冠心病介入治疗术后患者焦虑抑郁普遍存在,有可能增加了冠心病介入治疗术后患者MACE事件的发生。
Objective To investigate the relationship between anxiety and depression and the prognosis of coronary heart disease patients. Methods A total of 108 patients with coronary heart disease undergoing PCI were enrolled in this study. Patients were divided into two groups according to Hamilton Depression Inventory and Anxiety Scale. Patients were divided into two groups: anxiety and depression (group A) and control group (group B) The occurrence of MACE, the factors that affect the MACE events were compared and analyzed, anxiety and depression status and MACE events were analyzed by multivariate correlation. Results There were 31 cases (28.7%) of anxiety and depression (group A) and 77 cases (71.3%) of control group (group B). The incidence of MACE in group A (29.0%) was significantly higher than that in group B (15.6%) (P <0.01). Multivariate regression analysis showed that anxiety and depression, diabetes, hypertension, smoking Was an independent predictor of MACE events (anxiety and depression, OR = 0.921, 95% confidence interval 0.845-0.963, P = 0.022). Conclusion Anxiety and depression are common in patients after coronary intervention, which may increase the occurrence of MACE after coronary intervention.