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目的阐明法洛四联症（ＴＯＦ）晚期室性心律失常的发生率及与严重程度有关的因素，以防止晚期猝死，改善术后远期疗效。方法本组随访４９例ＴＯＦ纠治术后病例，包括心电图、２４小时动态心电图（Ｈｏｌｔｅｒ）、二维超声心动图（２ＤＥ）。结果猝死１例（２％），４８例经Ｈｏｌｔｅｒ检查：室性心律失常２１例（４３．８％），有临床意义的室性心律失常（改良Ｌｏｗｎ分类法≥２级者）７例（１４．６％）。≥２级的病例术时年龄、随访时年龄、随访时间均大于＜２级病例（有统计学意义）。而与体外循环时间、主动脉阻断时间、残余分流、残余梗阻无关。结论结果表明早期进行ＴＯＦ根治术是防止术后晚期猝死的关键。Ｈｏｌｔｅｒ监测高危室性心律失常是有价值的。
Objective To clarify the incidence of late ventricular arrhythmia and the factors related to the severity of tetralogy of Fallot (TOF) in order to prevent sudden death in the late stage and to improve the long-term effect after operation. Methods The group was followed up 49 cases of TOF after surgery, including ECG, 24-hour Holter, 2DE. One case (2%) died of sudden death and 48 cases were diagnosed by Holter. There were 21 cases (43.8%) of ventricular arrhythmias, 7 cases (14 cases) with clinically significant ventricular arrhythmia .6%). Grade 2 cases were age, follow-up, age and follow-up time were greater than <2 cases (statistically significant). And with cardiopulmonary bypass time, aortic occlusion time, residual shunt, residual obstruction has nothing to do. Conclusion The results show that the early TOF radical mastectomy is the key to prevent sudden postoperative death. Holter monitoring of high-risk ventricular arrhythmias is valuable.