论文部分内容阅读
目的通过回顾性分析,探讨儿童脑干不同部位胶质瘤的治疗。方法对5年间可随访的、经MRI影像学证实为脑干胶质瘤的33例患儿进行分析,男19例、女14例,肿瘤位于中脑顶盖区2例,中脑3例,桥脑17例,延髓3例,位于中脑桥脑5例、桥脑延髓2例,桥延髓颈髓1例,将患者分成手术组、放疗组、未治疗组。结果手术组15例有7例存活,术后生存期17～52个月,8例死亡,术后存活1.5～12个月;放疗组7例有4例死亡,存活期分别为2、4、11、24个月,3例存活3、7.5、17个月。结论不同部位的儿童脑干胶质瘤应采取个体化的治疗,其中顶盖胶质瘤伴发脑积水应行脑脊液转流术,局灶性外生性或肿瘤表面脑组织少的局灶性内生性行手术治疗,而弥漫性者行放疗。
Objective To retrospectively analyze the treatment of glioma in different parts of brain stem in children. Methods A total of 33 children, including 19 males and 14 females, who were followed up for 5 years and confirmed by MRI as brain stem gliomas, were located in the middle cerebral region in 2 cases, midbrain in 3 cases, There were 17 cases of pontine and 3 cases of medulla oblongata. Among them, there were 5 cases of midbrain pons, 2 cases of medulla oblongata and 1 case of medulla oblongata. The patients were divided into operation group, radiotherapy group and untreated group. Results In the operation group, 7 cases survived in 15 cases, the survival time was 17-52 months, 8 cases died and 1.5- 12 months postoperatively. In 7 cases of radiotherapy group, 4 cases died and the survival time was 2, 4, 11,24 months, 3 cases survived 3,7.5,17 months. Conclusions Individual brainstem gliomas in different parts of the brain should be treated individually. The glomerulus with capsular hydrocephalus should be treated by cerebrospinal fluid flow, focal exogeneity or focal brain tissue on the surface of the tumor Endogenous surgical treatment, while diffuse radiotherapy.