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目的比较泮托拉唑与奥美拉唑治疗急性脑血管病并发应激性溃疡出血的临床疗效。方法选取三垛中心卫生院司徒分院于2013年3月—2016年3月收治的急性脑血管病并发应激性溃疡出血患者84例,随机将患者分为观察组与对照组,各42例。观察组患者采用泮托拉唑治疗,对照组患者采用奥美拉唑治疗。比较两组患者临床疗效、不良反应发生情况。结果观察组患者总有效率高于对照组,差异有统计学意义(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论泮托拉唑较奥美拉唑治疗急性脑血管病并发应激性溃疡出血的临床疗效更加明显,可有效缓解患者出血症状。
Objective To compare the clinical efficacy of pantoprazole and omeprazole in the treatment of acute cerebrovascular disease complicated with stress ulcer bleeding. Methods Eighty-four patients with acute cerebrovascular disease complicated with acute ulcer bleeding were selected from Stuart Hospital of Sanchu Central Hospital from March 2013 to March 2016, and the patients were randomly divided into observation group and control group with 42 cases in each group. Patients in the observation group were treated with pantoprazole, and patients in the control group were treated with omeprazole. The clinical efficacy and adverse reactions of the two groups were compared. Results The total effective rate of observation group was higher than that of control group, the difference was statistically significant (P <0.05). Two groups of patients with adverse reactions, the difference was not statistically significant (P> 0.05). Conclusions Pantoprazole is more effective than omeprazole in the treatment of acute cerebrovascular disease complicated by stress ulcer bleeding, which can effectively relieve the bleeding symptoms in patients.