低功率毫米波辐射对小鼠肝脏作用的实验研究

来源 :第四军医大学学报 | 被引量 : 0次 | 上传用户:haolong12345
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本实验应用频率为36.04及50.05GHz,功率密度为1mW/cm~2的毫米波,照射小鼠腹部体表,发现低功率毫米波辐射对小鼠肝脏有间接作用。应用透射电镜及电镜细胞化学技术观察发现,肝细胞超微结构呈轻微可逆性损伤,G-6-P酶含量增多;应用扫描图象分析仪(TAS)对组织化学染色的肝组织切片进行DNA定量,发现DNA含量无显著性变化。通过动态观察表明,两种不同频率的毫米波对肝细胞的影响不同,线粒体及G-6-P酶对36.04 GHz的毫米波较敏感,而内质网对50.05GHz的毫米波较敏感。根据实验结果,本文对毫米波特异性效应的机理进行了探讨,指出该效应可能是通过神经-体液系统介导的。 In this experiment, the frequency of 36.04 and 50.05GHz, the power density of 1mW / cm ~ 2 millimeter wave irradiation on the body surface of mice abdomen and found that low-power millimeter wave radiation on mouse liver has an indirect effect. Using transmission electron microscopy and electron microscopy cytochemistry techniques found that the ultrastructure of liver cells showed a slight reversible injury, G-6-P enzyme content increased; the use of scanning image analyzer (TAS) on histochemical staining of liver tissue DNA Quantitative and found no significant changes in DNA content. Dynamic observations showed that the effects of two different frequencies of millimeter wave on hepatocytes were different. Mitochondria and G-6-P enzyme were sensitive to 36.04 GHz millimeter wave, while endoplasmic reticulum was more sensitive to 50.05 GHz millimeter wave. Based on the experimental results, the mechanism of millimeter-wave-specific effects is discussed in this paper, suggesting that this effect may be mediated through neuro-humoral systems.
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