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目的分析单纯胆囊切除术与根治性切除术治疗Ⅱ期胆囊癌远期疗效差异。方法选择2012年11月—2013年11月在本院接受治疗的Ⅱ期胆囊癌患者作为研究对象,随机分为接受单纯胆囊切除术的对照组患者及接受根治性切除术的观察组患者各43例。随访5年分析二组患者的生存时间及各年生存率、生活质量评分等差异。结果①接受手术治疗后,观察组患者的中位生存期明显长于对照组患者,且其术后1年、3年及5年的累积生存率也大幅高于对照组患者(P<0.05);②接受手术治疗后,观察组患者的远期平均生活质量评分明显高于对照组患者,且生活质量评分优良率明显高于对照组患者(P<0.05)。结论根治性胆囊切除术可以更为有效的延长胆囊癌患者的生存时间,提高远期生存率并改善其生活质量,较单纯胆囊切除术具有明显优势。
Objective To analyze the long-term curative effect of simple cholecystectomy and radical resection on stage Ⅱ gallbladder cancer. Methods Patients with stage II gallbladder cancer treated in our hospital from November 2012 to November 2013 were randomly divided into control group receiving cholecystectomy and observation group receiving radical resection example. Five years follow-up analysis of two groups of patients with the survival time and the annual survival rate, quality of life scores and other differences. Results ① The median survival time of the observation group was significantly longer than that of the control group after operation. The cumulative survival rates at 1 year, 3 years and 5 years after operation were significantly higher than those in the control group (P <0.05). ② After surgery, the long-term average quality of life scores of the observation group were significantly higher than those of the control group, and the excellent and good quality of life quality score was significantly higher than that of the control group (P <0.05). Conclusion radical cholecystectomy can be more effective in patients with gallbladder cancer survival time and improve long-term survival and improve their quality of life, compared with simple cholecystectomy has obvious advantages.